Madonna's first Grammy nomination was for 1985's "Crazy for You," her first win was not until 1992 and she won no significant Grammys until 1999 (for Ray of Light). To date, she has nine wins and, by my count, 30 nominations. (At the rate she's going, Katy Perry should surpass that in an album or so...)
This year, the Grammy nominations failed to include her for her Sticky & Sweet Long Form Music Video—even though it was quite a spectacular show not to mention the #1 solo tour of all time.
But David Guetta was nominated for his remixing services on "Revolver," a song a lot of Madonna's fans despise (I still like it, sorry!).
Here is his Grammy-nominated remix, the "One Love Club Remix":